Predicate: transfect

Roleset id: transfect.01 , introduce nucleic acids into a recipient cell, Source: , vncls: , framnet:


transfect (v.)
transfection (n.)


        For Bio-AMR annotations.
        Arg0-PAG: intentional agent of transfection (e.g. scientist)
        Arg1-PPT: recipient of transfection (e.g. cell)
        Arg2-PPT: entity inserted into the cell (e.g. nucleid acid)

Example: example with agent

        To establish that the cloned protein displays serine racemase activity, we transfected HEK293 cells that do not possess endogenous D-serine.

        Arg0: we
        Rel: transfected
        Arg1: HEK293 cells that do not possess endogenous D-serine

Example: example with instrument

        In cells transfected with wild-type EGFR, MEK inhibition led to feedback activation of phospho-ERBB3 and phosho-EGFR, recapitulating the results we had observed in our panel of cancer cell lines (Figure 6A).

        Arg1: cells
        Rel: transfected
        Arg2: wild-type EGFR