Predicate: transfect
Roleset id: transfect.01 , introduce nucleic acids into a recipient cell, Source: , vncls: , framnet:
Aliases:
| Alias | FrameNet | VerbNet |
|---|
| transfect (v.) | | |
| transfection (n.) | | |
Roles:
For Bio-AMR annotations.
Arg0-PAG: intentional agent of transfection (e.g. scientist)
Arg1-PPT: recipient of transfection (e.g. cell)
Arg2-PPT: entity inserted into the cell (e.g. nucleid acid)
Example: example with agent
To establish that the cloned protein displays serine racemase activity, we transfected HEK293 cells that do not possess endogenous D-serine.
Arg0: we
Rel: transfected
Arg1: HEK293 cells that do not possess endogenous D-serine
Example: example with instrument
In cells transfected with wild-type EGFR, MEK inhibition led to feedback activation of phospho-ERBB3 and phosho-EGFR, recapitulating the results we had observed in our panel of cancer cell lines (Figure 6A).
Arg1: cells
Rel: transfected
Arg2: wild-type EGFR