Predicate: abrogate

Roleset id: abrogate.01 , block a biological process or function, Source: , vncls: , framnet:

abrogate.01: ABROGATE-V NOTES: Created for Bio-AMR annotations.

Aliases:

AliasFrameNetVerbNet
abrogate (v.)
abrogation (n.)

Roles:

        Arg0-PAG: intentional agent of abrogation (e.g. scientist)
        Arg1-PPT: thing abrogated, blocked
        Arg2-MNR: instrument

Example: abrogate-v: active use

        Cleavage site mutations in the encephalomyocarditis virus P3 region lethally abrogate the normal processing cascade.

        Arg0: Cleavage site mutations in the encephalomyocarditis virus P3 region
        Argm-mnr: lethally
        Rel: abrogate
        Arg1: the normal processing cascade

Example: abrogate-v: with agent

        By treating cells with RUNX2 siRNA, we abrogated the Wip1-dependent activation of Bax expression and the cells sensitization to cis-platin.

        Argm-mnr: By treating cells with RUNX2 siRNA
        Arg0: we
        Rel: abrogate
        Arg1: the Wip1-dependent activation of Bax expression and the cells sensitization to cis-platin

Example: abrogation-n

        Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis.

        Rel: Abrogation
        Arg1: of TGF beta signaling
        Argm-loc: in mammary carcinomas