frustrate-v; 2 Senses

Sense Number 1: cause feelings of annoyance and ineffectiveness

Her boss's short-sighted decisions frustrated Helen.
Silly delays have always frustrated me.
He was frustrated by his inability to draw a straight line.

VerbNet: amuse-31.1
FrameNet: Experiencer_obj
PropBank: frustrate.01
WordNet 3.0 Sense Numbers: 2

Sense Number 2: impede, thwart

This frustrated the attempts of corrupt polititians to stack the department in their favor.
These barriers have long frustrated the efforts of healthcare providers to improve their services.

VerbNet: NM
FrameNet: Preventing,Thwarting
PropBank: NM
WordNet 3.0 Sense Numbers: 1