Predicate: ubiquitinate

Roleset id: ubiquitinate.01 , ubiquitinate, Source: , vncls: , framnet:

ubiquitinate.01: UBIQUINATE-V NOTES: Created for Bio-AMR annotations.

Aliases:

AliasFrameNetVerbNet
ubiquitinate (v.)
ubiquitination (n.)

Roles:

        Arg0-PAG: agent of ubiquitination (e.g. scientist)
        Arg1-PPT: thing ubiquitinated
        Arg2-MNR: instrument
        Arg3-PRD: result of ubiquitination

Example: ubiquitinate-v: active use

        We ubiquitinated bacterially expressed GST-TRAF6 with Lys63-linked chains using the in vitro ubiquitination reaction.

        Arg0: We
        Rel: ubiquitinated
        Arg1: bacterially expressed GST-TRAF6
        Arg2: with Lys63-linked chains
        Argm-mnr: using the in vitro ubiquitination reaction

Example: ubiquitinate-v: with result

        [A sizable proportion of the histone H2A and H2B pool]-1 is ubiquitinated *-1 to form uH2A and uH2B in interphase ceils.

        Rel: ubiquitinated
        Arg1: *-1
        Arg3: to form uH2A and uH2B
        Argm-loc: in interphase ceils

Example: ubiquination-n

        Hypoxia inhibits the ubiquination of HIF-1alpha

        Rel: ubiquination
        Arg1: of HIF-1alpha