Roleset id: hyperphosphorylate.01 , phosphorylate fully, so that all potential phosphorylation sites are occupied, Source: , vncls: , framnet:
Aliases:
Alias
FrameNet
VerbNet
hyperphosphorylate (v.)
hyperphosphorylation (n.)
Roles:
For Bio-AMR annotations. Arg0-PAG: intentional agent of hyperphosphorylation (e.g. scientist) Arg1-PPT: thing hyperphosphorylated (e.g. protein or another organic molecule) Arg2-MNR: instrument (e.g. enzyme) Arg3-PRD: result of hyperphosphorylation
Example: example with agent
If we hyperphosphorylate eIF4E-binding protein 1, this stops it binding to eIF4E.
Arg0: we Arg1: eIF4E-binding protein 1
Example: example with result
The pre-mRNA has to reach a length of 25 nt before the C-terminal end of RNAP II can be hyperphosphorylated to form the elongation complex.
Arg1: C-terminal end of RNAP II Arg3: elongation complex
Example: example with instrument
HSV-1 serine/threonine kinase US3 hyperphosphorylates IRF3 and inhibits the IFN-β production (P1413).