The patient described a pain in his chest.
Mary took a pain pill for her strained back muscles.
Amputees report feeling pain in their phantom limbs.
The dentist gave John some Novacaine so he wouldn't feel any pain.
She said the labor pains are becoming more intense.
The economy must go through this pain and suffering to regain its health. (figurative extension)
WordNet 3.0 Sense Numbers: 1, 3
She is in a lot of emotional pain after her divorce.
He knew the pain of loneliness growing up as an only child.
The protagonist of the film wants to avoid the pain of rejection at all costs.
WordNet 3.0 Sense Numbers: 2
NOTE: refers to a person
Mary's pre-teen son can be such a pain at times!
The customs guys can really be a pain in the neck when they want to.
WordNet 3.0 Sense Numbers: 4
John thinks shoveling his driveway is a real pain.
This infestation of winter moths has become a real pain in New England.
It'll be a big pain to have to retype all these forms into the computer.
WordNet 3.0 Sense Numbers: 5
NOTE: occurs in the plural in idiomatic phrases, 'take pains', 'at pains',
Sally took great pains to ensure that the package would arrive on Bob's birthday.
For all our pains we didn't even get a thank you.
He was at pains to measure up to his brother's accomplishments.
Pete took real pains to get us this bottle of aged port.
WordNet 0.0 Sense Numbers: 2
NOTE: usually in the phrase 'on pain of X' or 'under pain of X'
They were required to keep silent under pain of court martial.
Don't touch her collection of china dolls on pain of death!
WordNet 0.0 Sense Numbers: 1